FREAK N HUGE® works positively in different ways on your genetics. Here are the 10 Hyper-Growth technologies included in FREAK N HUGE® that will help your genetics reach another level.

1- VasoTrex® Nitrate: a precision NO enhancing formula. It consists only from the latest scientifically proven ingredients for Massive Vasodilation of your body. This multistage ratio provides you with the prolonged vessels stretchiness that providing a beneficial transport of all active ingredients of FREAK N HUGE®. Arginine Alpha Ketoglutarate stimulates the production of nitric oxide in your body. NO acts as your body's master "cell-signalling" molecule, directing and ordering a complex array of activities. It regulates blood flow significantly pumping up blood vessels, impacts muscle contraction, nerve signalling and muscle growth (1,2).


Reference:
1

Arginine HCL is another form of arginine that has high rate of absorption and provides supportive arginine source for even better Vasodilation (3).

Citrulline Malate is a potent combination of the amino acid citrulline and the organic salt malate, as an intermediate in the urea cycle, citrulline aids in the removal of endotoxins such as lactic acid and ammonia, which can impair exercise performance. By this property citruline speeds up your recovery (4, 5). It also can act as arginine precursor and provide a third element for NO levels’ amplification. These three elements provide a highly balanced NO-activation system. Furthermore, your organism decides by a distinctive prosses of a metabolic bidirectional pathway what amino acid to choose in order to start NO production. It worth to be mentioned, that this system has beneficial 2:1 ratio of arginine to citruline.

L-Norvaline, a modified form of the branched-chain amino acid valine, is a supportive ingredient for the complex. It’s a key to unlock to (6). Agmatine Sulfate stimulates some types of nitric oxide synthase (NOS) while inhibiting others (7,8). It regulates the work of VasoTrex® Nitrate technology.

Though a range of biological processes these compounds provide higher NO production than any other supplementation or by your own body.

2- Next Level® Power Amplification: creatine is used by your muscle tissue for the production of phosphocreatine, an important factor in the formation of ATP, the source of energy for muscle contraction. The mix of the creatines in this technology provides a step-by step increase of ATP production, making sure that time of your biological energy storing “ceiling” limited by your genetics, completely brake by three creatines from MVP Biotech®. These creatines have a different rate of absorption and as a fact different rate of activity. Creatine Nitrate is first to take care about your energy storages, acting in a matter of minutes, providing a great push to ATP production. This high level of energy is supported by Creatine Ethyl Ester and Creatine Monohydrate afterwards.

From the genetics point of view there is no any more profound ATP enhancing ratio. This mix is leading to greater muscle size, strength and sports performance (1).

3- GlycoLoad Rx: technology with the best value of carbs. Carbs are the most important source of energy for all athletes, one gram of carbs provides you with four calories of energy.  GlycoLoad Rx™ technology provides you with adequate carbs uptake preventing protein from being used as energy through refilling your glycogen storages (9).

4- Prosulin® IV: a highly potential complex of four ingredients for total blood glucose levels regulation and increase of creatine uptake. The following ingredients are highly insulinotropic: L-Taurine, a highly promising agent for blood glucose regulation, helps you easily deal with carbs upload (10) and provides protection from some toxins that can accumulate in you body through training (11).

Cinnamon Bark Extract with the decreasing glucose intolerance increases creatine uptake by muscles with the help of carbs provided by GlycoLoad Rx (12, 13). The following two ingredients are responsible for high creatine level in your muscle.

Glycocyamine is a direct precursor of creatine. However the metabolism of creatine from glycocyamine in the liver causes a depletion of methyl groups, this causes homocysteine levels to rise. For lowering these negative levels, betaine is used in Prosulin® IV formula (14).



Reference: 2-3-4-5-6-7-8

5- High Impact® Glutamine: a multistage complex of the most effective forms of amino acid, glutamine. Glutamine is the most abundant amino acid in muscle tissue, however, with a training its levels can decrease.  Despite of many physiological actions, glutamine affects glycogen, the secondary energy storage, accumulation in muscles (15).  Carbs from GlycoLoad Rx™ along with these glutamines totally promote storages of muscle glycogen (16).

6- BCAA-NITRO Plex™: a vitaland highly ranked complex of branched-chain amino acids maintenances of muscle tissue and preserve muscle stores of glycogen delivered by GlycoLoad Rx™ (17). BCAAs provide a beneficial effect on performance, reducing fatigue and raising energy levels (18,19,20).  The scientifically proven ratio of BCAAs becomes even better through superior nitrate form of these of branched-chain aminos that can completely break your genetics by providing increase of muscle mass.

7- ProTN8 Matrix: is our new multi-release, 8-stage, nitrogen-rich protein technology - consisting of 8 precision multi stage proteins amalgamated designed for slow, medium, and fast amino acids and peptides delivery. Each of the proteins provides a unique and complimentary profile of amino acids and absorption rates, ensuring that your muscles never run out of protein building blocks. This translates fast and long lasting nitrogen delivery for immediate and extended protein synthesis for your muscle (*).

8- Mega Pro-M Minerals and Mega Pro-V ® Vitamins: a unique complex of two technologies which contain Fat-soluble and Water-soluble vitamins, as well as, Major and Trace minerals. The variety of physiological action that happen with the assistance of vitamins and minerals is quite great. They play key roles in the metabolism of carbohydrates and fats providing fuel for your muscles. They act like cofactors for metabolic enzymes which regulates energy metabolism and protein synthesis (21, 22).



Reference: 9 - 10

9- Lipolytix & OMEGA EdgeMatrix: FREAK N HUGE® delivers significant percent of its calories from a scientifically determined blend of designer fatty acids. This highly potent mix serves biological functions, including improving testosterone output and promoting the production of good prostaglandins, which improve insulin function. Also, scientifically designed fats promote a powerful carb-sparing effect, which provides numerous mass-gaining benefits.
MCTs function as an energy source. They promote the oxidation of fat over carbohydrate and help regulate appetite. EFAs (essential fatty acids) are not produced by the body and must be consumed in order to prevent deficiency. MVP Biotech® delivers highest potency and purity essential fatty acids.

Lipid compound of the complex provides your body with fuel for intense energy and thermogenic calories that support fat burning to make you leaner (*).

10- FibeX: a specially design complex of Fibers supports gastrointestinal health, increasing the surface area that the body can absorb nutrients across, which increases nutrient uptake and utilization. This most balanced complex aids in digesting all of the protein and carbs you need to get Freak n Huge and stay Freak n Huge (*).

* Powered by MVP Science

Taking FREAK N HUGE® with healthy diet can make up for your genetics. Your genes, which you inherited from your parents, contain the biological programs that control your muscle mass, endurance, strength. But you don't have to be at their mercy. FREAK N HUGE®’s Hyper-Growth Technologies enable your genes to function at their best thus providing maximum results. You can't change your genetics, but taking FREAK N HUGE®, along with healthy diet and other supplement from MVP Biotech®, helps your genes achieve their full potential. FREAK N HUGE® is the highly potent “gene therapy” that helps you achieve continuous hardcore workouts with tremendous results.

References:

1. Little JP et al.  For. Creatine, arginine alpha-ketoglutarate, amino acids, and medium-chain triglycerides and endurance and performance. Int J Sport Nutr Exerc Metab. 2008 Oct; 18(5):493-508.
2. Grange RW et al. Nitric oxide contributes to vascular smooth muscle relaxation in contracting fast-twitch muscles. Physiol Genomics. 2001 Feb 7; 5(1):35-44.
3. Bode-Böger SM et al. L-arginine-induced vasodilation in healthy humans: pharmacokinetic-pharmacodynamic relationship. Br J Clin Pharmacol. 1998 Nov; 46(5):489-97.
4. Bendahan D et al. Citrulline/malate promotes aerobic energy production in human exercising muscle. Br J Sports Med. 2002 Aug; 36(4):282-9.
5. Pérez-Guisado J, Jakeman PM. Citrulline malate enhances athletic anaerobic performance and relieves muscle soreness. J Strength Cond Res.  2010 May; 24(5):1215-22.
6. Chang CI et al. Arginase modulates nitric oxide production in activated macrophages. Am J Physiol. 1998 Jan; 274.
7. Gao Y et al. Agmatine: a novel endogenous vasodilator substance. Life Sci. 1995; 57(8):PL83-6.
8. Abe K, Abe Y, Saito H. Agmatine suppresses nitric oxide production in microglia. Brain Res. 2000 Jul 28; 872(1-2):141-8.
9. The Position Statement from the Dietitians of Canada, the American Dietetic Association, and the American College of Sports Medicine, Canadian Journal of Dietetic Practice and Research in the Winter of 2000, 61(4):176-192.
10. Franconi F et al. Plasma and platelet taurine are reduced in subjects with insulin-dependent diabetes mellitus: effects of taurine supplementation. Am J Clin Nutr. 1995 May; 61(5):1115-9.
11. Timbrell JA, Seabra V, Waterfield CJ. The in vivo and in vitro protective properties of taurine. Gen Pharmacol. 1995 May; 26(3):453-62.
12. Imparl-Radosevich et al. Regulation of PTP-1 and insulin receptor kinase by fractions from cinnamon: implications for cinnamon regulation of insulin signalling. Horm Res. 1998 Sep; 50(3):177-82.
13. Green et al. Carbohydrate ingestion augments skeletal muscle creatine accumulation during creatine supplementation in humans. Am J Physiol.  1996 Nov; 271(5 Pt 1):E821-6.
14. Schwab et al. Betaine supplementation decreases plasma homocysteine concentrations but does not affect body weight, body composition, or resting energy expenditure in human subjects. Am J Clin Nutr. 2002 Nov; 76(5):961-7.
15. Varnier M et al. Stimulatory effect of glutamine on glycogen accumulation in human skeletal muscle. Am J Physiol.  1995 Aug; 269 (2 Pt 1):E309-15.
16. Bowtell et al. Effect of oral glutamine on whole body carbohydrate storage during recovery from exhaustive exercise. J Appl Physiol. 1999 Jun; 86(6):1770-7.
17. Blomstrand E, Ek S, Newsholme EA. Influence of ingesting a solution of branched-chain amino acids on plasma and muscle concentrations of amino acids during prolonged submaximal exercise. Nutrition.  1996 Jul-Aug; 12(7-8):485-90.
18. Hassmén P et al. Branched-chain amino acid supplementation during 30-km competitive run: mood and cognitive performance. Nutrition.  1994 Sep-Oct; 10(5):405-10.
19. Blomstrand E et al. Influence of ingesting a solution of branched-chain amino acids on perceived exertion during exercise. Acta Physiol Scand. 1997 Jan; 159(1):41-9.
20. Blomstrand E et al. Administration of branched-chain amino acids during sustained exercise--effects on performance and on plasma concentration of some amino acids. Eur J Appl Physiol Occup Physiol. 1991; 63(2):83-8.
21. Volpe SL. Vitamins, minerals, and exercise. In: Sports Nutrition: A Practice Manual for Professionals. 4th ed. Sports, Cardiovascular, and Wellness Nutritionists Dietetic Practice Group. Dunford M, ed. American Dietetic Association. 2006:61–93.
22. Fogelholm M. Vitamin, mineral, and antioxidant needs of athletes. In: Burke L, Deakin V. Clinical Sports Nutrition. 3rd ed. McGraw-Hill, 2006:313–353.


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